Long back in summer of 1999 in the small town Michigan, there were four friends who lived their life happily and they began a pursuit of losing their virginity. They had a great time of their life with this new Adventure. Thirteen years later after they graduated from high school all the friends are well settled in their lives. Jim, Paul, Chris, Kevin and Steve are well established and have a successful career. Jim and Michelle are the married but unhappy couple.
Chris lives in with his girlfriend Mia while Kevin is married to Ellie and is very happy. Stifler is travelling the world in search of his true love. One of their classmates organizes a Reunion for his batch mates. Now all these friends come home grown into adults to recollect the memories and relive all the moments and in this journey they get inspired by the hormonal teenagers who launched a legend of Comedy.